Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I

Membrane-type matrix metalloproteinase I (MT1-MMP)-deficient mice were found to have severe defects in skeletal development and angiogenesis. The craniofacial, axial, and appendicular skeletons were severely affected, leading to a short and domed skull, marked deceleration of postnatal growth, and d...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Zhou, Zhongjun, Apte, Suneel S., Soininen, Raija, Cao, Renhai, Baaklini, George Y., Rauser, Richard W., Wang, Jianming, Cao, Yihai, Tryggvason, Karl
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18145/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10737763/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.060037197
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