Amikacin and gentamicin accumulation pharmacokinetics and nephrotoxicity in critically ill patients.
Twenty-five critically ill adults receiving blood level-adjusted doses of amikacin were prospectively studied with serum, urine, and, when possible, tissue amikacin concentrations. These data were fitted to a two-compartment pharmacokinetic model. Prolonged urine collections or postmortem tissues (o...
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| Published in: | Antimicrob Agents Chemother |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
1981
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181374/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7247354/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.19.1.147 |
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