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Inhibition of hepatitis B virus deoxyribonucleic acid polymerase by the 5'-triphosphates of 9-beta-D-arabinofuranosyladenine and 1-beta-D-arabinofuranosylcytosine.

9-beta-D-Arabinofuranosyladenine (ara-A), 1-beta-D-arabinofuranosylcytosine (ara-C), and their 5'-triphosphates (ara-ATP and ara-CTP) were tested for ability to inhibit the hepatitis B virus (HBV)-associated deoxyribonucleic acid (DNA) polymerase. Ara-C did not inhibit the HBV DNA polymerase at the...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Hess, G, Arnold, W, Meyer zum Büschenfelde, K H
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1981
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181355/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6166246/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.19.1.44
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