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Activation of gene expression by small molecule transcription factors

Eukaryotic transcriptional activators are minimally comprised of a DNA binding domain and a separable activation domain; most activator proteins also bear a dimerization module. We have replaced these protein modules with synthetic counterparts to create artificial transcription factors. One of thes...

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Hlavní autoři: Mapp, Anna K., Ansari, Aseem Z., Ptashne, Mark, Dervan, Peter B.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC18119/
https://ncbi.nlm.nih.gov/pubmed/10760265
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