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A novel method for the evaluation of proximal tubule epithelial cellular necrosis in the intact rat kidney using ethidium homodimer

BACKGROUND: Ethidium homodimer is a cell-membrane impermeant nuclear fluorochrome that has been widely used to identify necrotic cells in culture. Here, we describe a novel technique for evaluating necrosis of epithelial cells in the proximal tubule that involves perfusing ethidium homodimer through...

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Main Authors: Edwards, Joshua R, Diamantakos, Evangelos A, Peuler, Jacob D, Lamar, Peter C, Prozialeck, Walter C
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1810561/
https://ncbi.nlm.nih.gov/pubmed/17319948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6793-7-1
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