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Systemic inflammation and neurodegeneration in a mouse model of multiple sulfatase deficiency
Sulfatases are involved in several biological functions such as degradation of macromolecules in the lysosomes. In patients with multiple sulfatase deficiency, mutations in the SUMF1 gene cause a reduction of sulfatase activities because of a posttranslational modification defect. We have generated...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1810506/ https://ncbi.nlm.nih.gov/pubmed/17360554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700382104 |
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