Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma

Recent studies have identified stem cells in brain cancer. However, their relationship to normal CNS progenitors, including dependence on common lineage-restricted pathways, is unclear. We observe expression of the CNS-restricted transcription factor, OLIG2, in human glioma stem and progenitor cells...

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Autori principali: Ligon, Keith L., Huillard, Emmanuelle, Mehta, Shwetal, Kesari, Santosh, Liu, Hongye, Alberta, John A., Bachoo, Robert M., Kane, Michael, Louis, David N., DePinho, Ronald A., Anderson, David J., Stiles, Charles D., Rowitch, David H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1810344/
https://ncbi.nlm.nih.gov/pubmed/17296553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2007.01.009
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