Both Fcγ and complement receptors mediate transfer of immune complexes from erythrocytes to human macrophages under physiological flow conditions in vitro

Abnormal clearance by the mononuclear phagocytic system of immune complexes (IC) is important in the pathogenesis of systemic lupus erythematosus (SLE). We have developed an in vitro model to investigate the cellular mechanisms involved in the transfer of soluble IC from erythrocytes to human macrop...

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Autors principals: Hepburn, A L, Mason, J C, Wang, S, Shepherd, C J, Florey, O, Haskard, D O, Davies, K A
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2006
Matèries:
Basic Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809732/
https://ncbi.nlm.nih.gov/pubmed/16968408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2006.03174.x
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