In the rat, citrullinated autologous fibrinogen is immunogenic but the induced autoimmune response is not arthritogenic

Conversion of arginyl to citrullyl residues (citrullination) is essential for the formation of the epitopes recognized by rheumatoid arthritis (RA)-associated autoantibodies to citrullinated proteins (ACPA). ACPA are secreted by plasma cells of the rheumatoid synovial tissue where their major target...

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Detalhes bibliográficos
Main Authors: Duplan, V, Foulquier, C, Clavel, C, Al Badine, R, Serre, G, Saoudi, A, Sebbag, M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Animal Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809699/
https://ncbi.nlm.nih.gov/pubmed/16907920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2006.03168.x
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