The Toll-like receptor 4 (Asp299Gly) polymorphism is a risk factor for Gram-negative and haematogenous osteomyelitis

Osteomyelitis is a bone infection caused mostly by Staphylococcus aureus but also by Gram-negative bacteria. Toll-like receptors (TLRs), after recognizing microbial products, induce a signal in neutrophils, leading to NF-κB activation and transcription of pro-inflammatory genes. Polymorphisms in TLR...

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Autors principals: Montes, A H, Asensi, Victor, Alvarez, Victoria, Valle, Eulalia, Ocaña, M G, Meana, A, Carton, J A, Paz, Jose, Fierer, J, Celada, A
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2006
Matèries:
Clinical Studies
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809620/
https://ncbi.nlm.nih.gov/pubmed/16487238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2005.03002.x
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