Immunomodulation using the recombinant monoclonal human B7-DC cross-linking antibody rHIgM12

A patient with Waldenstrom's macroglobulinaemia expresses a high titre IgM antibody in serum that binds both mouse and human dendritic cells (DC) in a B7-DC (PD-L2)-dependent manner. We have reported previously that purified antibody from patient serum activates immature and mature DC in vitro,...

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Detalhes bibliográficos
Main Authors: Van Keulen, V P, Ciric, B, Radhakrishnan, S, Heckman, K L, Mitsunaga, Y, Iijima, K, Kita, H, Rodriguez, M, Pease, L R
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Clinical Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809594/
https://ncbi.nlm.nih.gov/pubmed/16412056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2005.02992.x
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