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Multiple interleukin-18 injections promote both mouse Th1 and Th2 responses after sublethal Escherichia coli infection

Interleukin (IL)-18 is considered to induce exclusively the Th1 immune response but not the Th2 response in the presence of adequate IL-12 stimulation in bacterial infections. However, we demonstrate herein that multiple IL-18 injections to the mice not only enhance the early Th1 response but also s...

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Autors principals: Kinoshita, M, Kuranaga, N, Matsumoto, A, Ono, S, Shinomiya, N, Hiraide, H, Seki, S
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809554/
https://ncbi.nlm.nih.gov/pubmed/16367932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2005.02973.x
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