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Defective prevention of immune precipitation in autoimmune diseases is independent of C4A*Q0

Increased prevalence of C4 null alleles is a common feature of autoimmune diseases. We have shown previously that complement-dependent prevention of immune precipitation (PIP) is defective in patients with systemic lupus erythematosus (SLE), and correlated this defect with C4A*Q0 and low levels of t...

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Autors principals: Arason, G J, Kolka, R, Hreidarsson, A B, Gudjonsson, H, Schneider, P M, Fry, L, Arnason, A
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809379/
https://ncbi.nlm.nih.gov/pubmed/15932521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2005.02794.x
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