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The role of tumour necrosis factor in the kinetics of lipopolysaccharide-mediated neutrophil priming in whole blood

Neutrophils can be primed by bacterial lipopolysaccharide (LPS) for an enhanced oxidative burst, which is a key element in the pathogenesis of Gram-negative sepsis. Some serum proteins (e.g. lipopolysaccharide-binding protein) avidly bind LPS and markedly enhance receptor binding and cellular activa...

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Autors principals: van Leeuwen, H J, Van Der Tol, M, Van Strijp, J A G, Verhoef, J, van Kessel, K P M
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809339/
https://ncbi.nlm.nih.gov/pubmed/15762876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2005.02748.x
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