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Mitoxantrone induces cell death in peripheral blood leucocytes of multiple sclerosis patients

Mitoxantrone (MX) is a cytotoxic drug with proven clinical efficacy in active multiple sclerosis (MS). In this ex vivo study we investigated the immunological effects of MX on peripheral blood leucocytes (PBL) from MS patients. PBL were isolated from 46 patients with active MS (mean age 42 years, fe...

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Autors principals: Chan, A, Weilbach, F X, Toyka, K V, Gold, R
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809264/
https://ncbi.nlm.nih.gov/pubmed/15606626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2005.02653.x
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