Imbalance between interleukin-1 agonists and antagonists: relationship to severity of inflammatory bowel disease

Interleukin (IL)-1 is a key mediator in the pathogenesis of inflammatory bowel disease (IBD). Naturally occurring IL-1 modulators include IL-1 receptor antagonist (IL-1Ra), IL-1 soluble receptor Type I (IL-1sRI), IL-1sRII and IL-1 receptor accessory protein (AcP). Systemic and mucosal levels of IL-1...

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Bibliographische Detailangaben
Hauptverfasser: LUDWICZEK, O, VANNIER, E, BORGGRAEFE, I, KASER, A, SIEGMUND, B, DINARELLO, C A, TILG, H
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2004
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809217/
https://ncbi.nlm.nih.gov/pubmed/15498044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02599.x
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