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Expression of Werner and Bloom syndrome genes is differentially regulated by in vitro HIV-1 infection of peripheral blood mononuclear cells

In HIV infection, continuous immune activation leads to accelerated ageing of the adaptive immune system, similar to that observed in elderly people. We investigated the expression of WRN and BLM (genes involved in disorders characterized by premature ageing, genomic instability and cancer predispos...

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Detalhes bibliográficos
Main Authors: BORDI, L, AMENDOLA, A, CICCOSANTI, F, ABBATE, I, CAMILLONI, G, CAPOBIANCHI, M R
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809202/
https://ncbi.nlm.nih.gov/pubmed/15498034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02622.x
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