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Peripheral blood T cell responses to keratin peptides that share sequences with streptococcal M proteins are largely restricted to skin-homing CD8(+) T cells

The association of psoriasis with Streptococcus pyogenes throat infections suggests a potential antigenic target for the T cells that are known to infiltrate psoriatic skin. Streptococcal M protein share an extensive sequence homology with the human epidermal keratins. Keratin 17 (K17), while being...

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Detalhes bibliográficos
Main Authors: JOHNSTON, A, GUDJONSSON, J E, SIGMUNDSDOTTIR, H, LOVE, T J, VALDIMARSSON, H
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809187/
https://ncbi.nlm.nih.gov/pubmed/15373909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.00600.x
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