A novel and effective approach of developing aggressive experimental autoimmune gastritis in neonatal thymectomized BALB/c mouse by polyinosinic:polycytidylic acid

Neonatal thymectomy induces autoimmune gastritis (AIG) in 40–70% of BALB/c mice. We presumed that induction of autoimmunity by polyinosinic:polycytidylic acid (poly I:C) might allow development of a more aggressive model of AIG. A group of BALB/c mice were thymectomized on day 3 after birth. Neonata...

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Bibliographic Details
Main Authors: KOBAYASHI, Y, MURAKAMI, H, AKBAR, S M F, MATSUI, H, ONJI, M
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2004
Subjects:
Animal Studies
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809059/
https://ncbi.nlm.nih.gov/pubmed/15147343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02467.x
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