GAD65 antibody isotypes and epitope recognition during the prediabetic process in siblings of children with type I diabetes

We observed 42 initially non-diabetic siblings of affected children to characterize the humoral immune response to the 65 kDa isoform of glutamic acid decarboxylase (GAD65) in preclinical type I diabetes. During the observation period with a mean duration of 9·6 years 21 siblings progressed to type...

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Hauptverfasser: HOPPU, S, RONKAINEN, M S, KULMALA, P, ÅKERBLOM, H K, KNIP, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2004
Schlagworte:
Clinical Studies
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809002/
https://ncbi.nlm.nih.gov/pubmed/15030523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02416.x
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