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Coupling of oral human or porcine insulin to the B subunit of cholera toxin (CTB) overcomes critical antigenic differences for prevention of type I diabetes

Our earlier investigations have demonstrated a critical difference in the efficacy of orally administered porcine compared to human or mouse insulin (no effect) in preventing type I diabetes in two distinct experimental models. Based on these findings one has to assume that certain insulins might no...

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Detalhes bibliográficos
Main Authors: PETERSEN, J S, BREGENHOLT, S, APOSTOLOPOLOUS, V, HOMANN, D, WOLFE, T, HUGHES, A, DE JONGH, K, WANG, M, DYRBERG, T, VON HERRATH, M G
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808831/
https://ncbi.nlm.nih.gov/pubmed/12974752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2003.02255.x
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