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Delivery of antigen in allogeneic cells preferentially generates CD4(+) Th1 cells

We have examined the possibility of evoking antigen-specific T cell immune response by using allogeneic cells as a source of adjuvant and also as a vehicle to deliver antigen. The mice were immunized with different preparations of antigen-pulsed allogeneic and syngeneic splenocytes. It was observed...

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Bibliographic Details
Main Authors: AGREWALA, J N, SUVAS, S, SINGH, V, VOHRA, H
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808824/
https://ncbi.nlm.nih.gov/pubmed/12974749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2003.02254.x
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