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Functional and molecular aspects of transient T cell unresponsiveness: role of selective interleukin-2 deficiency

Defects of T cell (Tc) proliferation have been demonstrated in several autoimmune diseases. Detailed mechanisms governing activation and proliferation of Tc are still not completely known. Here we show that under certain conditions human peripheral blood lymphocytes, once activated by anti-CD3, fail...

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Detalhes bibliográficos
Main Authors: KÖLLER, M D, KIENER, H P, ARINGER, M, GRANINGER, W B, MEUER, S, SAMSTAG, Y, SMOLEN, J S
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808700/
https://ncbi.nlm.nih.gov/pubmed/12699409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2003.02150.x
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