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Relevance of differential immunogenicity of human and mouse recombinant desmoglein-3 for the induction of Acantholytic autoantibodies in mice

Pemphigus vulgaris (PV) is an antibody-mediated autoimmune disease of the skin and mucous membranes. Desmoglein-3 (dsg-3) expressed in the suprabasal layer of the skin serves as an autoantigen in PV. Passive transfer of sera, either from patients with PV or from experimental animals immunized with a...

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Detalhes bibliográficos
Main Authors: KAITHAMANA, S, FAN, J-L, MEMAR, O, LI, K, UITTO, J, SEETHARAMAIAH, G S, PRABHAKAR, B S
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808684/
https://ncbi.nlm.nih.gov/pubmed/12653831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2003.02135.x
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