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Increased expression of the secretory leukocyte proteinase inhibitor in Wegener's granulomatosis

The secretory leucocyte proteinase inhibitor (SLPI) is a low molecular weight, tissue-specific inhibitor of proteases, such as elastase and cathepsin G. It is the major local protease inhibitor in the upper airways. Proteinase 3, the main autoantigen in Wegener's granulomatosis (WG), can degrad...

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Autors principals: OHLSSON, S, FALK, R, YANG, J J, OHLSSON, K, SEGELMARK, M, WIESLANDER, J
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Inc 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808594/
https://ncbi.nlm.nih.gov/pubmed/12519404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2003.02024.x
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