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Myosin VIIA Defects, which Underlie the Usher 1B Syndrome in Humans, Lead to Deafness in Drosophila

In vertebrates, auditory and vestibular transduction occurs on apical projections (stereocilia) of specialized cells (hair cells). Mutations in myosin VIIA (myo-VIIA), an unconventional myosin, lead to deafness and balance anomalies in humans, mice, and zebra-fish; individuals are deaf, and stereoci...

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Main Authors: Todi, Sokol V., Franke, Josef D., Kiehart, Daniel P., Eberl, Daniel F.
Format: Artigo
Jezik:Inglês
Izdano: 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808204/
https://ncbi.nlm.nih.gov/pubmed/15886106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2005.03.050
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