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Penetration of cefixime into fibrin clots and in vivo efficacy against Escherichia coli, Klebsiella pneumoniae, and Staphylococcus aureus.

The experimental model of infected fibrin clots in rabbits was used to study the penetration and in vivo activity of cefixime against Klebsiella pneumoniae, Escherichia coli, and Staphylococcus aureus. The respective MICs of cefixime against these strains were 0.25, 2, and 8 micrograms/ml. The clots...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Bergeron, M G, Turcotte, A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180618/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3545070/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.30.6.913
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