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Delayed treatment with combinations of antiviral drugs in mice infected with herpes simplex virus and application of the median effect method of analysis.

Mice were inoculated intracerebrally with a lethal dose of herpes simplex virus type 2. Three days later, the mice were treated intraperitoneally, twice daily for 4 days, with the following drugs alone or in combination: acyclovir (ACV), vidarabine (ara-A), 2'-fluoro-5-iodoaracytosine (FIAC), and 2'...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Schinazi, R F, Chou, T C, Scott, R T, Yao, X J, Nahmias, A J
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1986
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180586/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3777913/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.30.3.491
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