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Membrane perturbation by aminoglycosides as a simple screen of their toxicity.

A simple test to assess the toxicity of aminoglycosides was designed based on the interaction of these drugs with phosphatidylinositol bisphosphate. The fluorescent probe 1-anilino-8-naphthalene sulfonate was incorporated into liposomes composed of L-alpha-phosphatidylcholine and phosphatidylinosito...

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Bibliografische gegevens
Hoofdauteurs: Au, S, Weiner, N, Schacht, J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1986
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC180567/
https://ncbi.nlm.nih.gov/pubmed/3777905
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