Nalaganje...
Functional effects of naturally occurring KCNJ11 mutations causing neonatal diabetes on cloned cardiac K(ATP) channels
ATP-sensitive K(+) (K(ATP)) channels are hetero-octamers of inwardly rectifying K(+) channel (Kir6.2) and sulphonylurea receptor subunits (SUR1 in pancreatic β-cells, SUR2A in heart). Heterozygous gain-of-function mutations in Kir6.2 cause neonatal diabetes, which may be accompanied by epilepsy and...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Blackwell Science Inc
2006
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1805653/ https://ncbi.nlm.nih.gov/pubmed/16339180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.099168 |
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