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Large-scale fluid/fluid phase separation of proteins and lipids in giant plasma membrane vesicles

The membrane raft hypothesis postulates the existence of lipid bilayer membrane heterogeneities, or domains, supposed to be important for cellular function, including lateral sorting, signaling, and trafficking. Characterization of membrane lipid heterogeneities in live cells has been challenging in...

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Huvudupphovsmän: Baumgart, Tobias, Hammond, Adam T., Sengupta, Prabuddha, Hess, Samuel T., Holowka, David A., Baird, Barbara A., Webb, Watt W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2007
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805587/
https://ncbi.nlm.nih.gov/pubmed/17360623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611357104
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