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Serial analysis of chromatin occupancy identifies β-catenin target genes in colorectal carcinoma cells
Most instances of colorectal cancer are due to abnormalities in the Wnt signaling pathway, resulting in nuclear accumulation of β-catenin. β-Catenin activates transcription of target genes primarily by associating with the T cell factor/lymphoid enhancer-binding factor (TCF/Lef) family of transcript...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1805576/ https://ncbi.nlm.nih.gov/pubmed/17360646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611576104 |
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