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Serial analysis of chromatin occupancy identifies β-catenin target genes in colorectal carcinoma cells

Most instances of colorectal cancer are due to abnormalities in the Wnt signaling pathway, resulting in nuclear accumulation of β-catenin. β-Catenin activates transcription of target genes primarily by associating with the T cell factor/lymphoid enhancer-binding factor (TCF/Lef) family of transcript...

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Detalhes bibliográficos
Main Authors: Yochum, Gregory S., McWeeney, Shannon, Rajaraman, Veena, Cleland, Ryan, Peters, Sandra, Goodman, Richard H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805576/
https://ncbi.nlm.nih.gov/pubmed/17360646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611576104
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