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Monitoring the function of membrane transport proteins in detergent-solubilized form

Transport proteins constitute ≈10% of most proteomes and play vital roles in the translocation of solutes across membranes of all organisms. Their (dys)function is implicated in many disorders, making them frequent targets for pharmacotherapy. The identification of substrates for members of this lar...

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Detalles Bibliográficos
Main Authors: Quick, Matthias, Javitch, Jonathan A.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2007
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805550/
https://ncbi.nlm.nih.gov/pubmed/17360689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609573104
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