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Multiple, targeted deficiencies in selectins reveal a predominant role for P-selectin in leukocyte recruitment

We extend our previous analyses of mice deficient in selectins by describing the generation and comparative phenotype of mice lacking one, two, or three selectins after sequential ablation of the murine genes encoding P-, E-, and L-selectins. All mice deficient in selectins are viable and fertile as...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Robinson, Stephen D., Frenette, Paul S., Rayburn, Helen, Cummiskey, Marge, Ullman-Culleré, Mollie, Wagner, Denisa D., Hynes, Richard O.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18054/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10500197/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.20.11452
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