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Lack of Adenomatous Polyposis Coli Protein Correlates with a Decrease in Cell Migration and Overall Changes in Microtubule Stability

Most sporadic colorectal tumors carry truncation mutations in the adenomatous polyposis coli (APC) gene. The APC protein is involved in many processes that govern gut tissue. In addition to its involvement in the regulation of β-catenin, APC is a cytoskeletal regulator with direct and indirect effec...

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Detalhes bibliográficos
Main Authors: Kroboth, Karin, Newton, Ian P., Kita, Katsuhiro, Dikovskaya, Dina, Zumbrunn, Jürg, Waterman-Storer, Clare M., Näthke, Inke S.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805109/
https://ncbi.nlm.nih.gov/pubmed/17192415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-03-0179
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