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The Unique-5 and -6 Motifs of ZO-1 Regulate Tight Junction Strand Localization and Scaffolding Properties

The proper cellular location and sealing of tight junctions is assumed to depend on scaffolding properties of ZO-1, a member of the MAGUK protein family. ZO-1 contains a conserved SH3-GUK module that is separated by a variable region (unique-5), which in other MAGUKs has proven regulatory functions....

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Bibliografiske detaljer
Main Authors: Fanning, Alan S., Little, Brent P., Rahner, Christoph, Utepbergenov, Darkhan, Walther, Zenta, Anderson, James M.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805089/
https://ncbi.nlm.nih.gov/pubmed/17182847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-08-0764
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