Comparison of the modes of antiviral action of 2'-nor-deoxyguanosine and its cyclic phosphate, 2'-nor-cyclic GMP.

The metabolisms of 9-(1,3-dihydroxy-2-propoxymethyl)guanine (2'NDG) and its cyclic phosphate, 9-[(2-hydroxy-1,3,2-dioxophosphorinan-5-yl) oxymethyl]guanine P-oxide (2'-nor-cGMP), were compared in cultures of primary rabbit kidney cells infected with herpes simplex virus type 1 (HSV-1). 2'-Nor-cGMP w...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Germershausen, J, Bostedor, R, Liou, R, Field, A K, Wagner, A F, MacCoss, M, Tolman, R L, Karkas, J D
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1986
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180495/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3015013/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.6.1025
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