Differential effect of impaired renal function on the kinetics of clavulanic acid and amoxicillin.

Amoxicillin and clavulanic acid are prescribed as a fixed drug combination. The purpose of the present study was to assess the influence of various degrees of renal insufficiency (glomerular filtration rate [GFR], less than 5 to greater than 75 ml/min per 1.73 m2) on the pharmacokinetics of amoxicil...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Horber, F F, Frey, F J, Descoeudres, C, Murray, A T, Reubi, F C
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1986
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180453/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3707111/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.4.614
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