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Protection against inhaled oxidants through scavenging of oxidized lipids by macrophage receptors MARCO and SR-AI/II

Alveolar macrophages (AMs) express the class A scavenger receptors (SRAs) macrophage receptor with collagenous structure (MARCO) and scavenger receptor AI/II (SRA-I/II), which recognize oxidized lipids and provide innate defense against inhaled pathogens and particles. Increased MARCO expression in...

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Main Authors: Dahl, Morten, Bauer, Alison K., Arredouani, Mohamed, Soininen, Raija, Tryggvason, Karl, Kleeberger, Steven R., Kobzik, Lester
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1804372/
https://ncbi.nlm.nih.gov/pubmed/17332894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29968
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