Successful treatment and prevention of murine Pneumocystis carinii pneumonitis with 4,4'-sulfonylbisformanilide.

Pneumocystis carinii pneumonitis was prevented in 0, 50, 100, and 100% of immunosuppressed rats given doses of 0.5, 5.0, 25.0, and 125.0 mg/kg (body weight) per day, respectively, of 4,4'-sulfonylbisformanilide (DFD). Therapeutic efficacy was demonstrated with DFD at 25.0 mg/kg per day, and when thi...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Hughes, W T, Smith, B L, Jacobus, D P
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1986
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180423/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3487287/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.3.509
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