Interaction of polycationic antibiotics with Pseudomonas aeruginosa lipopolysaccharide and lipid A studied by using dansyl-polymyxin.

A fluorescent derivative of polymyxin B (dansyl-polymyxin) was used to study the interaction of polycations with lipopolysaccharide (LPS) and lipid A from Pseudomonas aeruginosa. Dansyl-polymyxin became bound to LPS and lipid A sites, including Mg2+-binding sites, resulting in a 20-fold enhancement...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Moore, R A, Bates, N C, Hancock, R E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180420/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3013085/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.3.496
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