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Acyclic guanosine analogs as substrates for varicella-zoster virus thymidine kinase.

This study was performed to obtain information on the enzymatic background to the antiviral activity of acyclic guanosine analogs. Five acyclic guanosine analogs, the (R)- and (S)-enantiomers of 9-(3,4-dihydroxybutyl)guanine, 9-(4-hydroxybutyl)guanine, 9-[(2-hydroxyethoxy)methyl]guanine, and 9-[[2-h...

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Autores principales: Karlström, A R, Källander, C F, Abele, G, Larsson, A
Formato: Artigo
Lenguaje:Inglês
Publicado: 1986
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC180389/
https://ncbi.nlm.nih.gov/pubmed/3015002
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