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Effect of low-dose dopamine on the pharmacokinetics of tobramycin in dogs.

Low-dose dopamine or a placebo was given to six healthy mongrel dogs, each receiving tobramycin at 2.0 mg/kg on consecutive days in a randomized crossover fashion. Dopamine increased the total and renal clearances and elimination rate constant of tobramycin by 12.5, 20, and 25.9%, respectively, sugg...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Kirby, M G, Dasta, J F, Armstrong, D K, Tallman, R
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1986
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180388/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3729328/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.1.168
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