Comparative activities of UK-49,858 and amphotericin B against Blastomyces dermatitidis infections in mice.

UK-49,858, a new antifungal triazole derivative, was compared with amphotericin B in the treatment of pulmonary infections by Blastomyces dermatitidis in male BALB/cByJ mice. Administration of UK-49,858 in daily doses of 25 or 50 mg/kg for 21 days gave 30 and 100% survival rates, respectively. These...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Lyman, C A, Sugar, A M, Diamond, R D
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1986
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180385/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3015001/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.1.161
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