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Comparative activities of UK-49,858 and amphotericin B against Blastomyces dermatitidis infections in mice.

UK-49,858, a new antifungal triazole derivative, was compared with amphotericin B in the treatment of pulmonary infections by Blastomyces dermatitidis in male BALB/cByJ mice. Administration of UK-49,858 in daily doses of 25 or 50 mg/kg for 21 days gave 30 and 100% survival rates, respectively. These...

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Hlavní autoři: Lyman, C A, Sugar, A M, Diamond, R D
Médium: Artigo
Jazyk:Inglês
Vydáno: 1986
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC180385/
https://ncbi.nlm.nih.gov/pubmed/3015001
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