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Empirical vs Bayesian approach for estimating haplotypes from genotypes of unrelated individuals

BACKGROUND: The completion of the HapMap project has stimulated further development of haplotype-based methodologies for disease associations. A key aspect of such development is the statistical inference of individual diplotypes from unphased genotypes. Several methodologies for inferring haplotype...

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Hlavní autoři: Li, Shuying Sue, Cheng, Jacob Jen-Hao, Zhao, Lue Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1803795/
https://ncbi.nlm.nih.gov/pubmed/17261196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-8-2
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