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Polymorphisms of estrogen-biosynthesis genes CYP17 and CYP19 may influence age at menarche: a genetic association study in Caucasian females

Variation in age at menarche (AAM) is known to be substantially influenced by genetic factors, but the true causal genes remain largely unidentified. Because the increased amplitude of estrogen exposure of tissues initiates the onset of menarche, the genes involved in estrogen biosynthesis are natur...

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Hlavní autoři: Guo, Yan, Xiong, Dong-Hai, Yang, Tie-Lin, Guo, Yan-Fang, Recker, Robert R., Deng, Hong-Wen
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1803760/
https://ncbi.nlm.nih.gov/pubmed/16782804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddl155
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