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Influence of endotoxin on the intrarenal distribution of gentamicin, netilmicin, tobramycin, amikacin, and cephalothin.

Multiple factors may modify the pharmacokinetics of aminoglycosides and increase their nephrotoxic potential. In this study, we investigated the influence of Escherichia coli endotoxin on the renal handling of several aminoglycosides and one cephalosporin. Drug levels in the renal parenchyma, as wel...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Principais autores: Bergeron, M G, Bergeron, Y
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1986
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180354/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3524424/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.1.7
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