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Comparison of Itraconazole and Fluconazole Treatments in a Murine Model of Coccidioidal Meningitis

Coccidioidal meningitis (CM) is a devastating disease that requires long-term therapy and for which there is little hope of a cure. A model was used to compare the efficacies of itraconazole and fluconazole. CD-1 mice were infected intrathecally with 30 to 36 viable arthroconidia of Coccidioides. Or...

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Autors principals: Kamberi, Perparim, Sobel, Raymond A., Clemons, Karl V., Waldvogel, Andreas, Striebel, Joan M., Williams, Paul L., Stevens, David A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1803148/
https://ncbi.nlm.nih.gov/pubmed/17178793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00332-06
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