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Kinetics of gentamicin in plasma of nonpregnant, pregnant, and fetal guinea pigs and its distribution in fetal tissues.

Nonpregnant and pregnant guinea pigs in the last third of gestation were injected intramuscularly with 4 mg of gentamicin per kg, and drug concentrations in plasma were determined by radioimmunoassay at several intervals after injection. The maximum gentamicin concentration was lower in pregnant tha...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Lelievre-Pegorier, M, Sakly, R, Meulemans, A, Merlet-Benichou, C
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1985
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180306/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4073880/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.28.4.565
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