Antiviral activity of 5-ethyl-2'-deoxyuridine against herpes simplex viruses in cell culture, mice, and guinea pigs.

The susceptibility of 3 laboratory strains and 24 clinical isolates of herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) to 5-ethyl-2'-deoxyuridine was determined in plaque reduction assays in Vero cells. The median effective doses were 8.6 and 7.8 microM, respectively. The drug was less potent...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Schinazi, R F, Scott, R T, Peters, J, Rice, V, Nahmias, A J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1985
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180304/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3000291/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.28.4.552
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